2022
- SCREENflex stable cell line technologyIn: European Journal of Nuclear Medicine and Molecular Imaging
Preclinical evaluation of FAP-2286 for fibroblast activation protein targeted radionuclide imaging and therapy
- Immortalized Human Alveolar Epithelial cells On-ChipIn: Frontiers in Toxicology
A New Immortalized Human Alveolar Epithelial Cell Model to Study Lung Injury and Toxicity on a Breathing Lung-On-Chip System
2021
2020
2019
2018
- CI-SCREEN immortalisation technologyin: Nat Commun
Generation of multiple cell lines using our CI-SCREEN functional immortalisation technology and their detailed characterisation.
- Murine AELVi cellsin: ATLA
CI-SCREEN-mediated generation of murine Alveolar Epithelial Cells as a respiratory in vitro model.
- IFN response in INTEPI cellsin: Front. Immunol.
Characterisation of the IFN response in murine intestinal epithelial cells generated using our CI-SCREEN technology.
Lung macrophage scavenger receptor SR-A6 (MARCO) is an adenovirus type-specific virus entry receptor. Stichling N, et al., 2018 PLoS Pathog.
https://doi.org/10.1371/journal.ppat.1006914
Expansion of functional personalized cells with specific transgene combinations. Lipps C et al., 2018, Nat Commun.
http://www.nature.com/articles/s41467-018-03408-4
2017
Flagellin phase-dependent swimming on epithelial cell surfaces contributes to productive Salmonella gut colonisation. Horstmann JA et al., 2017, Cell Microbiol.
http://www.ncbi.nlm.nih.gov/pubmed/28295924
Proliferation status defines functional properties of endothelial cells. Lipps C et al., 2017, Cell Mol Life Sci.
http://www.ncbi.nlm.nih.gov/pubmed/27853834
Generation and characterization of two immortalized human osteoblastic cell lines useful for epigenetic studies. Pérez-Campo FM et al., 2017, J Bone Miner Metab.
http://www.ncbi.nlm.nih.gov/pubmed/27038990
2016
Human Alveolar Epithelial Cells Expressing Tight Junctions to Model the Air-Blood Barrier. Kuehn A et al., ALTEX. 2016; 33(3):251-60
http://www.ncbi.nlm.nih.gov/pubmed/26985677
IRAK-M Expression in Tumor Cells Supports Colorectal Cancer Progression through Reduction of Antimicrobial Defense and Stabilization of STAT3. Kesselring R et al., 2016, Cancer Cell.
http://www.ncbi.nlm.nih.gov/pubmed/27150039
2015
Type 1 fimbriae are important factors limiting the dissemination and colonization of mice by Salmonella Enteritidis and contribute to the induction of intestinal inflammation during Salmonella invasion. Kuzminska-Bajor et al., 2015, Front. Microbiol.
http://journal.frontiersin.org/article/10.3389/fmicb.2015.00276/full
Endothelial cell spheroids as a versatile tool to study angiogenesis in vitro. Heiss et al., 2015, The FASEB Journal.
http://www.fasebj.org/content/early/2015/04/09/fj.14-267633.abstract
2013
Generation of Mouse Small Intestinal Epithelial Cell Lines That Allow the Analysis of Specific Innate Immune Functions. Johannes Schwerk, Mario Köster, Hansjörg Hauser, Manfred Rohde, Marcus Fulde, Mathias W. Hornef, Tobias May. PLOS One 2013
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0072700
Eternity and functionality - rational access to physiologically relevant cell lines. Lipps C, May T, Hauser H, Wirth D. Biol Chem. 2013 Dec;394(12):1637-48.
http://www.ncbi.nlm.nih.gov/pubmed/23863696
Hepatitis C Virus Replication in Mouse Cells Is Restricted by IFN-Dependent and -Independent Mechanisms. Ramya Nandakumar, Katja Finsterbusch, Christoph Lipps, Berit Neumann, Martina Grashoff, Sharmila Nair, Inga Hochnadel, Stefan Lienenklaus, Ilka Wappler, Eike Steinmann, Hansjörg Hauser, Thomas Pietschmann, Andrea Kröger. Gastroenterology 2013
http://www.sciencedirect.com/science/article/pii/S0016508513012304
2012
Genetic aspects of cell line development from a synthetic biology perspective. Botezatu L, Sievers S, Gama-Norton L, Schucht R, Hauser H, Wirth D. Adv Biochem Eng Biotechnol. 2012
http://www.ncbi.nlm.nih.gov/pubmed/22068842
Funktionale Zelllinien durch neue Immortalisierungsprotokolle. May, T., Hauser, H., Wirth, D. BioSpektrum 2012 Volume 18, Issue 4, June 2012, Pages 390-393
http://link.springer.com/article/10.1007%2Fs12268-012-0199-3
2011
Rapid establishment of g-protein-coupled receptor-expressing cell lines by site-specific integration.Schucht R, Lydford S, Andzinski L, Zauers J, Cooper J, Hauser H, Wirth D, May T. J Biomol Screen. 2011
http://www.ncbi.nlm.nih.gov/pubmed/21335600
Integrated strategy for the production of therapeutic retroviral vectors. Carrondo M, Panet A, Wirth D, Coroadinha AS, Cruz P, Falk H, Schucht R, Dupont F, Geny-Fiamma C, Merten OW, Hauser H.Hum Gene Ther. 2011
http://www.ncbi.nlm.nih.gov/pubmed/21043806
2010
Retroviral vector performance in defined chromosomal Loci of modular packaging cell lines. Gama-Norton L, Herrmann S, Schucht R, Coroadinha AS, Löw R, Alves PM, Bartholomae CC, Schmidt M, Baum C, Schambach A, Hauser H, Wirth D. Hum Gene Ther. 2010
http://www.ncbi.nlm.nih.gov/pubmed/20222806
Recombinant protein expression by targeting pre-selected chromosomal loci. Nehlsen K, Schucht R, da Gama-Norton L, Krömer W, Baer A, Cayli A, Hauser H, Wirth D.BMC Biotechnol. 2009
http://www.ncbi.nlm.nih.gov/pubmed/20003421
Precise regulation of transgene expression level and control of cell physiology. Schucht R, Wirth D, May T. Cell Biol Toxicol. 2009
http://www.ncbi.nlm.nih.gov/pubmed/19763851
Road to precision: recombinase-based targeting technologies for genome engineering. Wirth D, Gama-Norton L, Riemer P, Sandhu U, Schucht R, Hauser H. Curr Opin Biotechnol. 2007
http://www.ncbi.nlm.nih.gov/pubmed/17904350
A new generation of retroviral producer cells: predictable and stable virus production by Flp-mediated site-specific integration of retroviral vectors. Schucht R, Coroadinha AS, Zanta-Boussif MA, Verhoeyen E, Carrondo MJ, Hauser H, Wirth D. Mol Ther. 2006
http://www.ncbi.nlm.nih.gov/pubmed/16697259
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