Functionally Immortalized

Thyroid Epithelial Cells

Thyroid epithelial cells (also known as follicular cells or thyrocytes) are the major cell type in the thyroid gland and are responsible for the production and secretion of the thyroid hormones triiodothyronine (T3) and thyroxine (T4). Using our CI-SCREEN technology (recently published in Nature Communications) we developed a novel immortal human thyroid epithelial cell line displaying a primary like phenotype. CI-huThyrECs are useful model system to study thyroid biology and disease, and to screen for endocrine disruptors.

Specifications of CI-huThyrEC

  • Expression of thyroid markers TG (Thyroglobulin) and TSHR (Thyroid Stimulating Hormone Receptor)
  • Maintain polarity (expression of ZO-1)
  • Functional cAMP response upon stimulation with TSH (Thyroid-stimulating hormone; also known as thyrotropin or thyrotropic hormone)

Following assays have been performed and validated with the CI-huThyrEC line:

  • TSHR functionality (cAMP regulation upon TSH stimulation)
Product NameCat. No.InformationPrice
Human Thyroid Epithelial Cells
INS-CI-1017Info Sheet / Instruction ManualGet prices

Related Products

Product NameCat. No.SizePrice
huThyrEC Medium (ready-to-use)INS-ME-1017500 ml€ 215.00
Epithelial Cell Coating SolutionINS-SU-1020-20ml20 ml€ 51.00
Epithelial Cell Coating SolutionINS-SU-1020-100ml100 ml (2x50ml)€ 195.00
Freezing mediumINS-SU-100430 ml€ 41.00

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