Functionally Immortalized

Microvascular Endothelial Cells

The endothelium is the thin layer of cells that lines the interior surface of blood vessels and lymphatic vessels, forming an interface between circulating blood or lymph in the lumen and the rest of the vessel wall. InSCREENeX currently offers human microvascular endothelial cells immortalized with the help of the CI-SCREEN technology. The technology and the characterization of the cell line is described in our recently published Nature Communications paper (Lipps et al., 2018).

Specifications of CI-huMEC

  • Typical surface marker expression (CD31, Tie1, Tie2, CD309)

Following assays have been performed and validated with the CI-huMEC cell line:

  • Tube formation matrigel
  • Acetylated LDL uptake
  • eNos activity
  • TNF-alpha stimulation
Product NameCat. No.InformationPrice
CI-huMEC,
Human microvascular endothelial cells
INS-CI-1008-Get prices

Related Products

Product NameCat. No.SizePrice
huMEC Medium (ready-to-use)INS-ME-1012500 ml€ 165.00
Gelatin solution 2%INS-SU-1015-50ml50 ml€ 27.80
Gelatin solution 2%INS-SU-1015-300ml6 x 50 ml€ 135.00
Freezing mediumINS-SU-100430 ml€ 29.20

Related Protocols for Cultivation of CI-huMEC

Literature

  • Expansion of functional personalized cells with specific transgene combinations. Lipps et al. 2018, Nature Communications [link]

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