Functionally Immortalized

Adult Intestinal Epithelial Cells

The intestine is responsible for the digestion and absorption of nutrients, but it also has secretory and immune functions. The intestinal epithelium, the most external layer of the mucosa, includes different cell types specilizing in different functions. In contrast to our CI-muINTEPI cells, CI-muADINTESTI are derived from adult tissue. If you start working on intestinal cells, we recommend using CI-muADINTESTI cells as a model system.

Specifications of CI-muADINTESTI

  • Organoid formation in 3D culture conditions
  • Expression of intestinal epithelial markers including ZO-1, E-cadherin, Muc2 and Lgr5
  • Barrier and tight junction formation on cell culture inserts

Following assays have been performed and validated with the CI-muADINTESTI line:

  • Barrier formation on cell culture inserts
  • Mucus secretion via Alcian Blue staining
  • Serotonin secretion
  • Organoid formation in Matrigel
  • Infection studies with EPEC
Product NameCat. No.InformationPrice
CI-muADINTESTI cells
Murine adult intestinal epithelial cells
INS-CI-1018Info sheetGet prices

Related Products

Product NameCat. No.SizePrice
muADINTESTI Medium (basal medium plus supplement)INS-ME-1023500 ml€ 170.00
Epithelial Cell Coating SolutionINS-SU-1020-20ml20 ml€ 45.00
Epithelial Cell Coating SolutionINS-SU-1020-100ml100 ml (2x50ml)€ 170.00
Freezing mediumINS-SU-100430 ml€ 35.00

Related documents for CI-muADINTESTI

Literature

  • Flagellin phase-dependent swimming on epithelial cell surfaces contributes to productive Salmonella gut colonisation. Horstmann JA et al., J. Cell Microbiol. 2017;19(8) [link]

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